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2,5-Dichloronicotinonitrile

CAS:

Ref. 3D-BFA95466

5g
547.00€
50g
2,640.00€
2,5-Dichloronicotinonitrile
Biosynth

Product Information

Name:2,5-Dichloronicotinonitrile
Brand:Biosynth
Description:2,5-Dichloronicotinonitrile is a phosphoinositide analog that has been shown to have cytotoxic effects in cancer cells. It binds to the phosphate groups on the cell membrane and inhibits the synthesis of phosphatidylinositol-3,4,5-trisphosphate (PIP3). This prevents the activation of Akt, which is a protein involved in cell survival and proliferation. The molecular modelling study showed that 2,5-Dichloronicotinonitrile can inhibit cancer cell proliferation at low nanomolar concentrations.
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Chemical properties

Molecular weight:173 g/mol
Formula:C6H2Cl2N2
Purity:Min. 95%

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