GSK 854
CAS: 1316059-00-3
Ref. 3D-BG165704
1mg | 310.00 € | ||
2mg | 465.00 € | ||
5mg | 740.00 € | ||
10mg | 1,102.00 € | ||
25mg | 1,971.00 € |
Product Information
- 3-([6-[(5-Chloro-2-pyridinyl)amino]-4-pyrimidinyl]amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide
Molecular probe for understanding the biology of troponin I-interacting kinase (TNNI3K) and its role in heart failure. The compound exhibits substantial selectivity for TNNI3K over homologous kinases B-Raf and EGFR. In vivo studies showed reduced ROS and p38 MAP kinase activation in mice models for myocardial infarction resulting in reduced left ventricular dysfunction and improved remodelling.
Chemical properties
Technical inquiry about: 3D-BG165704 GSK 854
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