Product Information
Name:GSK 854
Synonyms:
- 3-([6-[(5-Chloro-2-pyridinyl)amino]-4-pyrimidinyl]amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide
Brand:Biosynth
Description:Molecular probe for understanding the biology of troponin I-interacting kinase (TNNI3K) and its role in heart failure. The compound exhibits substantial selectivity for TNNI3K over homologous kinases B-Raf and EGFR. In vivo studies showed reduced ROS and p38 MAP kinase activation in mice models for myocardial infarction resulting in reduced left ventricular dysfunction and improved remodelling.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:482.97 g/mol
Formula:C18H19ClN6O4S2
Purity:Min. 95%
Technical inquiry about: GSK 854
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