Estimated delivery in United States, on Tuesday 18 Feb 2025
Product Information
Name:
GNE 140
Description:
Inhibitor of lactate dehydrogenase A (LDHA), which catalyzes the conversion of pyruvate to lactate yielding NAD. The compound binds to the enzymes active site adjacent to NADH with IC50 = 3 nM. LDHA is expressed in many glycolysis-dependent tumors and its inhibition affects global cell metabolism and proliferation.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
499.05 g/mol
Formula:
C25H23ClN2O3S2
Purity:
Min. 95%
InChI:
InChI=1S/C25H23ClN2O3S2/c26-20-3-1-2-4-22(20)33-23-21(29)15-25(27-24(23)30,18-9-14-32-16-18)17-5-7-19(8-6-17)28-10-12-31-13-11-28/h1-9,14,16,23H,10-13,15H2,(H,27,30)
InChI key:
InChIKey=GLDDJXYFHWRGPI-UHFFFAOYSA-N
SMILES:
O=C1CC(c2ccc(N3CCOCC3)cc2)(c2ccsc2)NC(=O)C1Sc1ccccc1Cl
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: 3D-BG166816 GNE 140
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