Product Information
- 5-Ethyl-5,6-dihydro-6-(2-hydroxy-4-methoxy-3,5-dimethyl-7-nonenyl)-2H-pyran-2-one
- Pa 48153C
- 2H-Pyran-2-one, 5-ethyl-5,6-dihydro-6-(2-hydroxy-4-methoxy-3,5-dimethyl-7-nonenyl)-, (5R-(5alpha,6alpha(2R*,3S*,4R*,5S*,7E)))-
- (5R,6R)-5-ethyl-6-[(2R,3S,4R,5S,7E)-2-hydroxy-4-methoxy-3,5-dimethylnon-7-en-1-yl]-5,6-dihydro-2H-pyran-2-one
Pironetin is a benzyl-containing natural product that inhibits the growth of leukemia cells in culture. It has a carbonic anhydrase inhibitory activity, which may be responsible for its antitumour activity. Pironetin is also shown to have anti-inflammatory properties by inhibiting the production of reactive oxygen species and tumor necrosis factor-α. The mechanism of this inhibition is not yet known. Pironetin also has carnitinease inhibitory activity and reacts with disulfides in proteins, resulting in protein degradation.
Chemical properties
Technical inquiry about: 3D-BGA51902 Pironetin
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