NAMI-A

CAS: 201653-76-1

Ref. 3D-BIA65376

Product Information

• Name: NAMI-A
• Synonyms: Ruthenate(1-), tetrachloro(1H-imidazole-κN3)[(sulfinyl-κS)bis[methane]]-, (OC-6-11)-, hydrogen, compd. with 1H-imidazole (1:1), Ruthenate(1-), tetrachloro(1H-imidazole-κN3)[1,1′-(sulfinyl-κS)bis[methane]]-, (OC-6-11)-, hydrogen, compd. with 1H-imidazole (1:1:1), 1H-Imidazole (OC-6-11)-tetrachloro(1H-imidazole-κN3)[1,1′-(sulfinyl-κS)bis[methane]]ruthenate(1-) (1:1), 1H-Imidazole, mono[(OC-6-11)-tetrachloro(1H-imidazole-κN3)[(sulfinyl-κS)bis[methane]]ruthenate(1-)]

Description

Nami-A is an experimental drug that has been shown to have significant cytotoxicity against carcinoma cell lines and solid tumours. Nami-A is a small molecule that binds to integrin receptors on the surface of cells, inhibiting the production of matrix metalloproteinase-9 (MMP-9). In vivo studies with Nami-A in mice showed that mitochondrial membrane potential was reduced and there was a decrease in redox potentials. The MMP-9 inhibition by Nami-A may be due to its ability to inhibit oxidative stress.

• Brand: Biosynth

Chemical properties

• Molecular weight: 458.18 g/mol
• Formula: C₈H₁₅Cl₄N₄OSRu
• Purity: Min. 95%