Product Information
GSK5959 is a modified heterocycle that binds to the bromodomains of the E3 ubiquitin ligase, preventing the ubiquitination and degradation of target proteins. This compound has been shown to inhibit proliferation in cells with low levels of p27Kip1 protein, which is involved in cell cycle arrest, and can be used as an anti-cancer agent. GSK5959 has also been shown to have a variety of other applications, including inhibition of phosphorylation at Thr638, Thr639, Thr641 and Ser643 on histone H3 (H3T6S) and inhibition of phosphorylation at Thr202/Thr205 on histone H2A (H2AT202/205).
Chemical properties
Technical inquiry about: 3D-BLB24565 GSK5959
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