Boc-Asp(OBzl)-OH

CAS: 7536-58-5

Ref. 3D-BLD-2059

Product Information

• Name: Boc-Asp(OBzl)-OH
• Synonyms: (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-4-oxo-4-phenylmethoxybutanoic acid, (2S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid, (2S)-4-(benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoate, (2S)-4-(benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid (non-preferred name), (S)-2-tert-Butoxycarbonylaminosuccinic acid 4-benzyl ester, (S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid, 4-(Benzyloxy)-2-[(Tert-Butoxycarbonyl)Amino]-4-Oxobutanoic Acid (Non-Preferred Name), 4-Benzylhydrogen-N-(tert-butoxycarbonyl)-L-aspartat, 4-benzyl hydrogen N-(tert-butoxycarbonyl)-L-aspartate, <span class="text-smallcaps">L</span>-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-(phenylmethyl) ester, Aspartic acid, N-carboxy-, 4-benzyl N-tert-butyl ester, <span class="text-smallcaps">L</span>-, Aspartic acid, N-carboxy-, 4-benzyl N-tert-butyl ester, L-, Boc-<span class="text-smallcaps">L</span>-Asp(OBn)-OH, Boc-L-aspartic acid 4-benzyl ester, Hydrogeno-N-(tert-butoxycarbonyl)-L-aspartate de 4-benzyle, L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-(phenylmethyl) ester, N-(tert-Butoxycarbonyl)aspartic acid β-benzyl ester, N-(tert-Butyloxycarbonyl)-<span class="text-smallcaps">L</span>-aspartic acid β-benzyl ester, N-(tert-Butyloxycarbonyl)-L-aspartic acid β-benzyl ester, N-(tert-Butyloxycarbonyl)-β-benzyl-<span class="text-smallcaps">L</span>-aspartic acid, N-(tert-Butyloxycarbonyl)-β-benzyl-L-aspartic acid, N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-aspartic acid 4-(phenylmethyl) ester, N-[(1,1-Dimethylethoxy)carbonyl]-L-aspartic acid 4-(phenylmethyl) ester, N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid 4-benzyl ester, N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid β-benzyl ester, N-tert-Butoxycarbonyl-L-aspartic acid 4-benzyl ester, N-tert-Butoxycarbonyl-L-aspartic acid β-benzyl ester, N-tert.-Butoxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid 4-phenylmethyl ester, hidrogeno-N-(terc-butoxicarbonil)-L-aspartato de 4-bencilo, β-Benzyl N-tert-butoxycarbonylaspartate

Description

Boc-Asp(OBzl)-OH is a cyclic peptide analog with an amino acid sequence homologous to the natural substrate of soybean trypsin. It has been shown to inhibit thrombin by intramolecular hydrogen bonding. Boc-Asp(OBzl)-OH has also been used as a prodrug for the synthesis of other analogs, such as Asp(OBzl)-Bz-NH2, which inhibits human immunodeficiency virus type 1 (HIV-1) protease. This inhibitor has been found to be effective in vitro and in vivo against HIV-1 strains that are resistant to other protease inhibitors, such as saquinavir, indinavir, and ritonavir.

• Brand: Biosynth

Chemical properties

• Molecular weight: 323.34 g/mol
• Formula: C₁₆H₂₁NO₆
• Purity: Min. 95%