Boc-Gly-OH

CAS: 4530-20-5

Ref. 3D-BLG-2054

Product Information

• Name: Boc-Gly-OH
• Synonyms: t-Butyloxycarbonyl-Glycine
• Brand: Biosynth
• Description: Boc-Gly-OH is a cyclic peptide with a fatty acid acyl chain. It is synthesized by reacting the amino acid glycine with sodium carbonate in the presence of trifluoroacetic acid to form the intermediate Boc-Gly-OSu. The product is then reacted with allyl bromide in a second step to produce Boc-Gly-OCH2CH2Br and then reacted with calcium chloride to yield the final product. Boc-Gly-OH has been used as an HIV inhibitor, which may be due to its ability to bind to both CD4 and gp120 proteins on the surface of HIV. This binding inhibits viral entry into host cells by blocking protease activity and fusion of viral envelope with host cell membrane, leading to inhibition of HIV infection.

Chemical properties

• Molecular weight: 175.18 g/mol
• Formula: C₇H₁₃NO₄
• Purity: Min. 95%