Boc-Arg(NO2)-OH

CAS: 2188-18-3

Ref. 3D-BLR-2058

Product Information

• Name: Boc-Arg(NO2)-OH
• Synonyms: (2S)-2-(tert-Butoxycarbonylamino)-5-[(N-nitrocarbamimidoyl)amino]pentanoic acid, (2S)-2-[[(tert-Butoxy)carbonyl]amino]-5-(N′-nitrocarbamimidamido)pentanoic acid, (2S)-5-[Amino(nitramido)methylidene]azaniumyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate, <span class="text-smallcaps">L</span>-Ornithine, N²-[(1,1-dimethylethoxy)carbonyl]-N⁵-[imino(nitroamino)methyl]-, Boc-Arg(No2), Boc-L-nitroarginine, N-Boc-N'-nitro-L-arginine, N²-[(1,1-Dimethylethoxy)carbonyl]-N⁵-[imino(nitroamino)methyl]-<span class="text-smallcaps">L</span>-ornithine, N²-tert-Butoxycarbonyl-N^G-nitroarginine, N²-tert-Butyloxycarbonyl-N^ω-nitro-<span class="text-smallcaps">L</span>-arginine, N^α-tert-Butoxycarbonyl-N^G-nitro-<span class="text-smallcaps">L</span>-arginine, N^α-tert-Butoxycarbonyl-N^G-nitroarginine, Ornithine, N²-carboxy-N⁵-(nitroamidino)-, N-tert-butyl ester, Ornithine, N²-carboxy-N⁵-(nitroamidino)-, N²-tert-butyl ester, <span class="text-smallcaps">L</span>-, Nα-tert-Butoxycarbonyl-NG-nitro-L-arginine, Ornithine, N2-carboxy-N5-(nitroamidino)-, N-tert-butyl ester, N2-[(1,1-Dimethylethoxy)carbonyl]-N5-[imino(nitroamino)methyl]-L-ornithine, L-Ornithine, N2-[(1,1-dimethylethoxy)carbonyl]-N5-[imino(nitroamino)methyl]-, Ornithine, N2-carboxy-N5-(nitroamidino)-, N2-tert-butyl ester, L-

Description

Boc-Arg(NO2)-OH is an activated molecule that is used as an anticoagulant. It inhibits the serine protease, which has an inhibitory effect on heparin-induced thrombocytopenia, and also inhibits platelet aggregation. Boc-Arg(NO2)-OH has been shown to have a potent inhibition of the enzyme that converts prothrombin into thrombin. This effect can be reversed by adding protamine sulfate. The clinical data suggest that this drug may be beneficial for patients with severe or life-threatening conditions who are taking heparin therapy or undergoing surgery and need anticoagulation. The prognosis of this drug is unclear, but it appears to be safe when administered in conjunction with other medications such as aspirin and warfarin.

• Brand: Biosynth

Chemical properties

• Molecular weight: 319.32 g/mol
• Formula: C₁₀H₁₉NO₄
• Purity: Min. 95%