Product Information
Name:OICR 9429
Synonyms:
- N-[2-(4-Methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide
Brand:Biosynth
Description:A highly selective WD repeat-containing protein 5 (Wdr5) antagonist and modulator of histone lysine methylation. The compound competitively disrupts the interaction between the Wdr5 and Wdr5-INteracting region (WIN) of methyltransferases. It inhibits the cell proliferation and restores differentiation in p30-dependent acute myeloid leukemia models.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:555.59 g/mol
Formula:C29H32F3N5O3
Purity:Min. 95%
InChI:InChI=1S/C29H32F3N5O3/c1-35-7-9-37(10-8-35)26-6-5-22(21-4-2-3-20(15-21)19-36-11-13-40-14-12-36)16-25(26)34-28(39)23-18-33-27(38)17-24(23)29(30,31)32/h2-6,15-18H,7-14,19H2,1H3,(H,33,38)(H,34,39)
InChI key:InChIKey=DJOVLOYCGXNVPI-UHFFFAOYSA-N
SMILES:CN1CCN(c2ccc(-c3cccc(CN4CCOCC4)c3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1
Technical inquiry about: OICR 9429
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