O8 OGG1 Inhibitor - Bio-X ™

CAS: 350997-39-6

Ref. 3D-BO167098

Product Information

• Name: O8 OGG1 Inhibitor - Bio-X ™
• Synonyms: 3,4-Dichloro-benzo[b]thiophene-2-carboxylic acid hydrazide, 3,4-Dichloro-1-benzothiophene-2-carbohydrazide, Benzo[b]thiophene-2-carboxylic acid, 3,4-dichloro-, hydrazide

Description

O8 OGG1 Inhibitor is a glycosylase enzyme that catalyses the conversion of guanine to xanthine. It is a key enzyme in the DNA repair mechanism called base excision repair or BER. This enzyme inhibits the hydrolysis of glycosidic bond required for the excision of 8-oxoguanine from double stranded DNA, which leads to accumulation of mutations. Additionally, it has been proposed as monotherapy for certain types of cancers. Furthermore, it has been seen to sensitise tumours for chemotherapy therefore research is being carried out to identify its potential to be used alongside cancer therapy.

O8 OGG1 Inhibitor is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

• Brand: Biosynth

Chemical properties

• Molecular weight: 261.13 g/mol
• Formula: C₉H₆Cl₂N₂OS
• Purity: Min. 95%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C9H6Cl2N2OS/c10-4-2-1-3-5-6(4)7(11)8(15-5)9(14)13-12/h1-3H,12H2,(H,13,14)
• InChI key: InChIKey=HSSHUDKWJRJKPV-UHFFFAOYSA-N
• SMILES: NNC(=O)c1sc2cccc(Cl)c2c1Cl