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ORN0829

CAS:

Ref. 3D-BO177707

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ORN0829
Biosynth

Product Information

Name:ORN0829
Brand:Biosynth
Description:ORN0829 is a novel, orally active, potent, and selective antagonist of serotonin 5-HT2A receptors. ORN0829 has been shown to inhibit the growth of human cancer cells in vitro and in vivo with a side-effect profile that is significantly less than other 5-HT2A antagonists currently in clinical development. ORN0829 also inhibits the binding of serotonin to 5-HT2A receptors and blocks the downstream signaling pathways of phospholipase C, protein kinase C, and mitogen-activated protein kinases.ORN0829 has an onset latency time of about 1 hour and its pharmacokinetic properties have been evaluated in both mice and rats. In these studies, ORN0829 was found to be well tolerated with no observed adverse effects.
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Chemical properties

Molecular weight:447.47 g/mol
Formula:C23H22FN7O2
Purity:Min. 95%

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