ORN0829

CAS: 2265899-49-6, 2265899-50-9

Ref. 3D-BO177707

Product Information

• Name: ORN0829
• Brand: Biosynth
• Description: ORN0829 is a novel, orally active, potent, and selective antagonist of serotonin 5-HT2A receptors. ORN0829 has been shown to inhibit the growth of human cancer cells in vitro and in vivo with a side-effect profile that is significantly less than other 5-HT2A antagonists currently in clinical development. ORN0829 also inhibits the binding of serotonin to 5-HT2A receptors and blocks the downstream signaling pathways of phospholipase C, protein kinase C, and mitogen-activated protein kinases.ORN0829 has an onset latency time of about 1 hour and its pharmacokinetic properties have been evaluated in both mice and rats. In these studies, ORN0829 was found to be well tolerated with no observed adverse effects.

Chemical properties

• Molecular weight: 447.47 g/mol
• Formula: C₂₃H₂₂FN₇O₂
• Purity: Min. 95%