Biotin-OSu

CAS: 35013-72-0

Ref. 3D-BOS-6003-PI

Product Information

• Name: Biotin-OSu
• Synonyms: D-Biotin-N-hydroxysuccinimide Ester, (+)-Biotinyl-N-hydroxysuccinimide, (N-Hydroxysuccinimidyl)biotin, 1-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}oxy)pyrrolidine-2,5-dione, 1-{[5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyl]oxy}pyrrolidine-2,5-dione, 1H-Thieno[3,4-d]imidazole, 2,5-pyrrolidinedione deriv., 1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, 2,5-dioxo-1-pyrrolidinyl ester, (3aS,4S,6aR)-, 2,5-Pyrrolidinedione, 1-[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]oxy]-, [3aS-(3aα,4β,6aα)]-, 2,5-Pyrrolidinedione, 1-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]oxy]-, <span class="text-smallcaps">D</span>-Biotin N-hydroxysuccinimide ester, Biotin N-hydroxysuccinimide, Biotin N-hydroxysuccinimidyl ester, Biotin NHS ester, Biotin succinimidyl ester, Biotin-Nhs, EZ-Link NHS-Biotin, Iotin-Nhs, N-Hydroxysuccinimidobiotin, N-Succinimidyl <span class="text-smallcaps">D</span>-biotinate, NHS Biotin, NSC 345668

Description

Biotin-OSu is a biotin derivative that is used as a fluorescence probe for the detection of DNA binding activity. It has been shown to bind to DNA with high affinity in an experimental model. Biotin-OSu binds to the major groove of DNA and can be used to detect dna binding activities, such as protein-DNA interactions, by forming a ternary complex with the target protein and a fluorophore. This compound has also been shown to react with mouse monoclonal antibodies and human serum proteins, which are transfer reactions. Biotin-OSu has also been used as a coupling agent in peptide hormones and streptavidin polymerase chain reactions (PCR). The presence of disulfide bonds in this compound give it stability but limits its solubility.

• Brand: Biosynth

Chemical properties

• Molecular weight: 341.39 g/mol
• Formula: C₁₄H₁₉N₃O₅S
• Purity: Min. 95%