Rituximab - 10mg/ml solution
CAS: 174722-31-7
Ref. 3D-BR167936
1mg | 664.00 € | ||
2mg | 904.00 € | ||
5mg | 1,702.00 € | ||
10mg | 2,604.00 € | ||
25mg | 4,512.00 € |
Product Information
Rituximab is a glycosylated monoclonal antibody that binds to the CD20 cell surface protein which is widely expressed on B-cells. Through the binding of rituximabs Fc portion, the antibody-dependent cellular cytotoxicity pathway (ADCC) and the complement-dependent cytotoxicity (CDC) pathway are initiated, both leading to B-cell lysis (Chisari, 2021). In addition, direct apoptosis can be the result of the inhibition of various B-cell signalling pathways. Rituximab is used in targeted therapy for chronic lymphocytic leukaemia (CLL), non-Hodgkin lymphoma (NHL) and some non-cancer pathologies, such as, multiple sclerosis (Johnson, 2001).
Chemical properties
Technical inquiry about: 3D-BR167936 Rituximab - 10mg/ml solution
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