Product Information
Name:Org-26576
Brand:Biosynth
Description:Org-26576 is a potent and selective antagonist of the neurotrophic receptor TrkB. It binds to the extracellular domain of human TrkB, blocking the interaction with its ligands, including brain-derived neurotrophic factor and basic fibroblast growth factor. Org-26576 has shown antidepressant effects in animal models of depression, but this effect is dose-dependent. The compound also inhibits glutamate neurotransmission by competitively blocking N-methyl D-aspartate receptors. Org-26576 has been shown to be safe for use in animals and humans, with no serious adverse events reported so far. Pharmacokinetic studies show that Org-26576 crosses the blood brain barrier and is rapidly absorbed after oral administration.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:204.23 g/mol
Formula:C11H12N2O2
Purity:Min. 95%
Technical inquiry about: Org-26576
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