Product Information
- (?R)-?-[[(5S)-5-[3-Chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(5-fluoro-2-furanyl)thieno[2,3-d]pyrimidin-4-yl]oxy ]-2-[[1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]methoxy]benzenepropanoic acid
- Benzenepropanoic acid, α-[[(5S)-5-[3-chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(5-fluoro-2-furanyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]methoxy]-, (αR)-
- (αR)-α-[[(5S)-5-[3-Chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(5-fluoro-2-furanyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]methoxy]benzenepropanoic acid
- S-63845
S 63845 is a novel anti-cancer drug that belongs to the class of ubiquitin ligases. It has been shown to induce apoptosis in cancer cells and inhibit tumor growth in vivo. S 63845 also inhibits the phosphorylation of cyclin D2, which may be a potential biomarker for sclerosing cholangitis (SCC). This compound is highly cytotoxic and has been found to be effective against subcutaneous tumors in mice. S 63845 also inhibits the proliferation of primary cells and has been shown to significantly reduce hepatic steatosis, as well as inhibiting inflammation caused by toll-like receptor 4 activation.
Chemical properties
Technical inquiry about: 3D-BS166833 S 63845
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