Product Information
Name:WS 383
Synonyms:
- 5-[[2-[[(4-Chlorophenyl)methyl]thio]-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]thio]-N,N-dimethyl-H-tetrazole-1-ethanamine
Brand:Biosynth
Description:Potent inhibitor of the interaction between defective cullin neddylation protein DCN1 and NEDD8-conjugating enzyme UBC12 with IC50 of 11 nM. WS 383 blocks the DCN1-UBC12 interaction in a reversible manner, selectively inhibits Cul3/1 neddylation and induces accumulation of p21, p27, and NRF2 proteins.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:462 g/mol
Formula:C18H20ClN9S2
Purity:Min. 95%
Technical inquiry about: WS 383
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