Product Information
- Phenethyl 3,4-dihydroxycinnamate
- 2-Phenylethyl 3-(3,4-Dihydroxyphenyl)-2-Propenoate
- 2-Phenylethyl 3-(3,4-Dihydroxyphenyl)Prop-2-Enoate
- 2-Phenylethyl caffeate
- 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 2-phenylethyl ester
- 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
- Caffeic acid phenethylester
- Phenethyl Caffeate
- β-Phenylethyl caffeate
Caffeic acid phenethyl ester (CAPE) is an active phenolic compound found in honeybee propolis that has the potential to downregulate inflammation in mammals. Studies demonstrated that CAPE specifically inhibits the protein complex NF?B - a key player in inflammation, associated with the pathogenesis of chronic inflammatory diseases. Moreover, CAPE inhibits the activity of the enzyme cyclooxygenase and the production of nitric oxide by macrophages, also responsible for inflammation. By acting on T cells, CAPE can reduce the production of pro-inflammatory cytokines and increase the production of anti-inflammatory ones, leading to a less overwhelming immune response to allergens.
Chemical properties
Technical inquiry about: 3D-C-1400 Caffeic acid phenethyl ester
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