Product Information
Ethyl 5-methyl-1H-pyrrole-3-carboxylate is a corticotropin-releasing factor (CRF) antagonist that has been shown to be an effective treatment for anxiety and depression. CRF antagonists are structurally related to the endogenous peptide, CRF, which regulates the hypothalamic-pituitary-adrenal axis. Ethyl 5-methyl-1H-pyrrole-3-carboxylate binds to the CRF receptor and blocks its activity, thus inhibiting the release of corticotropin from the pituitary gland. It is a bicyclic molecule that is closely related to other analogs such as alniditan, with similar properties. The discovery process of ethyl 5-methyl-1H-pyrrole-3 carboxylate was based on the synthesis of analogs with different structural features in order to find compounds that have a greater affinity for CRF receptors than
Chemical properties
Technical inquiry about: 3D-CAA19950 Ethyl 5-methyl-1H-pyrrole-3-carboxylate
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