MTT

CAS: 2348-71-2

Ref. 3D-CAA34871

Product Information

• Name: MTT
• Synonyms: 2,5-Diphenyl-3-(4,5-dimethylthiazol-2-yl)-2H-tetrazolium bromide, 2,5-Diphenyl-3-(4,5-dimethylthiazol-2-yl)tetrazolium bromide, 2-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2H-tetrazolium bromide, 2H-Tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide, 2H-Tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide (1:1), 3,[4,5-Dimethylthiazol-2-YL]-2,5-DIPHENYLTETRAZOLIUM BROMIDE, 3-(4,5-Dimethyl-2-THIAZOL-2-YL)-2,5-DIPHENYL-2H-TETRAZOLIUM BROMIDE, 3-(4,5-Dimethyl-2-THIAZOLYL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE, 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide, 3-(4,5-Dimethyl-2-thizolyl)-2,5-diphenyltertazolium bromide, 3-(4,5-Dimethylithiazolyl-2)-2,5-Diphenyl Monotetrazolium Bromide, 3-(4,5-Dimethylthiazol-2-YL)-2,5-DIPHYL-2 H-TETRAZOLIUM BROMIDE, 3-(4,5-Dimethylthiazol-2-Yl)-2,5-Diphenyl-2H-Tetrazoliumbromide, 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide, 3-(4,5-Dimethylthiazolyl)-2,5-diphenyl-2H-tetrazolium bromide, 3-(4,5-Dimethylthiazolyl)-2,5-diphenyltetrazolium bromide, 3-(4,5-Dimethylthiazolyl-2)-2,5-DIPHENYL TETRAZOLIUM BROMIDE, 3-(4,5-dimethyl-1,3-thiazol-2-yl)-2,5-diphenyl-2,3-dihydro-1H-tetrazol-1-ium bromide, 3-(4,5-dimethyl-1,3-thiazol-2-yl)-2,5-diphenyl-2H-tetrazol-3-ium bromide, 4,5-Dimethythiazoyl-Zyl2,5-Diphenylterrajolium Bromiole, MMT Tetrazolium, MTT tetrazolium, Methylthiazoletetrazolium, Mtt (1.11714), NSC 60102, Thiazolyl Blue, Thiazolyl Blue Monotetrazolium, Thiazolyl Blue tetrazolium bromide, Thiazolyl blue (Sigma)
• CAS: 2348-71-2

Description

MTT is a tetrazolium dye that is used to measure cell viability and metabolic activity in vitro. It is also used as a marker for assessing the cytotoxicity of anticancer drugs, antibiotics, and chemotherapeutic agents. MTT has been shown to induce autophagy in tumor cells, which may be due to its ability to decrease mitochondrial membrane potential and activate voltage-dependent calcium channels. MTT is toxic when injected into living animals and humans; therefore, it should be handled with care. The LD50 of intravenous administration in rats has been determined to be 1 g/kg body weight (mg/kg).

• Brand: Biosynth

Chemical properties

• Molecular weight: 415.3 g/mol
• Formula: C₁₈H₁₇BrN₅S
• Purity: Min. 95%