Quinoclamine

CAS: 2797-51-5

Ref. 3D-CAA79751

Product Information

• Name: Quinoclamine
• Synonyms: 06K-Quinone, 06K50W, 1,4-Naphthalenedione, 2-amino-3-chloro-, 1,4-Naphthoquinone, 2-Amino-3-Chloro-, 2-Amino-3-Chloro-1,4-Naphtoquinone, 2-Amino-3-Chloro-4-Naphthalenedione, 2-Amino-3-Chloro-4-Naphthoquinone, 2-Amino-3-Chloronaphthalene-1,4-Dione, 2-Amino-3-Chloronaphthoquinone, 2-Amino-3-chloro-1,4-dihydronaphthalene-1,4-dione, 2-Amino-3-chloro-1,4-naphthalenedione, 2-Chloro-3-Amino-1,4-Naphthoquinone, 3-Chloro-2-Amino-1,4-Naphthoquinone, Acnq, Mogeton, Mogeton G, Mogeton Granule, Mogetong, Mogetongranule, NSC 3910, NSC 642009, O 6K-Quinone, Quinoclamin, Timtec-Bb Sbb008204, 06K

Description

Quinoclamine is a redox-active film-forming polymer that has been shown to be effective against bacterial strains such as S. aureus, E. coli and B. subtilis. Quinoclamine inhibits the growth of bacteria by targeting their respiratory electron transport chain and reducing its activity. This leads to an accumulation of reactive oxygen species (ROS) in the cells which can cause oxidative stress, leading to cell death. Quinoclamine has also been shown to have antibacterial efficacy against Hl-60 cells and prevents the formation of carbonyl groups in mitochondria, which are toxic to cells. Quinoclamine is metabolized by cytochrome P450 enzymes into quinolinic acid, which is then converted into nicotinamide adenine dinucleotide phosphate (NADP+).

• Brand: Biosynth

Chemical properties

• Molecular weight: 207.61 g/mol
• Formula: C₁₀H₆ClNO₂
• Purity: Min. 95%