Product Information
- 1H-imidazole, 2-(methylsulfonyl)-
- 2-(Methylsulfonyl)-1H-imidazole
2-Methanesulfonyl-1H-imidazole (MSI) is a sulphydryl containing compound that has been shown to be an electron-withdrawing group. It has shown to be cytotoxic in the chinese hamster cell line and radiosensitizes cells in culture. MSI also inhibits oxidative phosphorylation by inhibiting enzymes such as eukaryotic cytochrome c oxidase, succinate dehydrogenase, and adenylate kinase. MSI is also effective against E. coli and other bacteria, including mycobacterium tuberculosis. MSI may be cytotoxic due to its ability to inhibit bacterial DNA synthesis by preventing deoxyribonucleotide synthesis and the inhibition of RNA synthesis.
Chemical properties
Technical inquiry about: 3D-CBA09898 2-Methanesulfonyl-1H-imidazole
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