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cis-4-Hydroxy-lomustine
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cis-4-Hydroxy-lomustine

CAS: 52049-26-0

Ref. 3D-CCA04926

1mg
364.00 €
2mg
517.00 €
5mg
801.00 €
10mg
1,160.00 €
25mg
2,087.00 €
Estimated delivery in United States, on Wednesday 8 Jan 2025

Product Information

Name:
cis-4-Hydroxy-lomustine
Description:

Cis-4-hydroxy-lomustine is a carbamylated prodrug that is converted to the active form, lomustine, by hydrolysis. It has high lipophilicity and is readily taken up by tissues. Cis-4-hydroxy-lomustine inhibits the growth of cancer cells by binding to DNA and blocking RNA synthesis. The drug also inhibits the activity of pyridinium crosslinks in proteins and nitroimidazole drugs in microorganisms. Cis-4-hydroxy-lomustine does not undergo extensive metabolism in the body, but undergoes rapid conversion to the active form, which is excreted mainly as unchanged drug in urine. Cis-4-hydroxy-lomustine has been shown to be effective against colorectal cancer cells with wild type p53 tumor suppressor gene and against small cell lung cancer cells with mutant p53 tumor suppressor

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
249.69 g/mol
Formula:
C9H16ClN3O3
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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