Product Information
- 4-Piperidinamine, 1-(6-chloro-2-pyridinyl)-, hydrochloride (1:1)
- 4-Piperidinamine, 1-(6-chloro-2-pyridinyl)-, monohydrochloride
- Cm 57277
- Sr 57227
- Sr 57227A
- [1-(6-Chloropyridin-2-yl)piperidin-4-yl]amine hydrochloride
SR 57227A is a 5-HT receptor antagonist. It binds to the serotonin 5-HT7 receptor and blocks the inhibitory effect of serotonin on locomotor activity and electrophysiological properties. SR 57227A also binds to the 5-HT4 receptor and blocks its inhibitory effect on cytosolic Ca2+. SR 57227A has a profile that is similar to that of piperidine hydrochloride, which is used as a pharmacological agent in humans. SR 57227A also has agonistic effects on the GABA receptors, which may be due to its ability to bind to the GABA receptor with high affinity.
Chemical properties
Technical inquiry about: 3D-CDA14561 SR 57227A
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