Product Information
- 4-(1-aminopropyl)-N,N,3-trimethylaniline
- 4-(2-aminopropyl)-N,N,3-trimethylaniline
- 4-(2-aminopropyl)-N,N,3-trimethylaniline dihydrochloride
- 4-(Dimethylamino)-alpha,2-dimethylphenethylamine
- 4-(Dimethylamino)-α,2-dimethylbenzeneethanamine
- Amiflamine
- Benzeneethanamine, 4-(dimethylamino)-alpha,2-dimethyl-
- Benzeneethanamine, 4-(dimethylamino)-α,2-dimethyl-
- Fla 336
4-(2-Aminopropyl)-N,N,3-trimethylaniline (4APTMA) is a drug that has been shown to be a 5-HT receptor antagonist. It binds to the 5HT1A receptor and inhibits its activity. 4APTMA can be used for the treatment of metabolic disorders such as obesity and bowel disease. The drug has also been shown to have inhibitory properties in animal models of inflammatory bowel disease, which may be due to its ability to block the uptake of serotonin into the brain.
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4APTMA is metabolized by CYP2D6 and CYP3A4 enzymes. It has also been shown that 4APTMA has an irreversible inhibition effect on dopamine uptake in a model system. This means that it prevents use of dopamine by binding to the transporter protein responsible for this action.
Chemical properties
Technical inquiry about: 3D-CDA50296 4-(2-Aminopropyl)-N,N,3-trimethylaniline
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