NSC12

CAS: 102586-30-1

Ref. 3D-CEA58630

Product Information

• Name: NSC12
• Brand: Biosynth
• Description: NSC12 is a potent inhibitor of cell proliferation and tumor growth. It has been shown to inhibit muscle cell proliferation and induce apoptotic cell death. NSC12 binds to the hydroxyl group of HIF-1α, which prevents it from forming a complex with the transcriptional coactivator p300. This binding inhibits the transcriptional activity of HIF-1α, leading to decreased protein synthesis in cells and ultimately apoptosis. NSC12 has been shown to be an effective therapeutic agent for proliferative diabetic retinopathy in an experimental model.

Chemical properties

• Molecular weight: 484.52 g/mol
• Formula: C₂₄H₃₄F₆O₃
• Purity: Min. 95%