Product Information
SB 204741 is a drug that blocks the action of serotonin receptors. It is used in the treatment of autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus. SB 204741 has been shown to reduce levels of cytosolic calcium, which may be due to its inhibition of phospholipase C. This drug also inhibits the polymerase chain reaction and slows cardiac muscle cell growth. In addition, it inhibits the release of growth factor-β1 from platelets and 5-hydroxytryptamine (5-HT) from synaptosomes in rat brain cells. SB 204741 also has a synergistic effect with detrusor muscle relaxants and potentiates the effects of selective 5-HT2C receptor antagonists on 5-HT2B receptors.
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