RS 25344 hydrochloride

CAS: 152815-28-6

Ref. 3D-CGA81528

Product Information

• Name: RS 25344 hydrochloride
• Brand: Biosynth
• Description: RS 25344 hydrochloride is a selective and activating phosphoinositide 3-kinase (PI3K) inhibitor. It has been shown to selectively inhibit the PI3K pathway, which is involved in cancer development and progression. RS 25344 hydrochloride induces cancer stem cells by inhibiting the activation of protein kinase B (Akt), which plays an important role in cell proliferation, differentiation, and apoptosis. In addition, this drug inhibits mesenchymal-epithelial transition by blocking the activation of the protein kinase C alpha (PKCα), which is involved in epithelial-mesenchymal transition. RS 25344 hydrochloride also induces cancer cells to transition from a stem cell phenotype into a non-stem cell phenotype by inhibiting the function of protein kinase A (PKA).

Chemical properties

• Molecular weight: 411.8 g/mol
• Formula: C₁₉H₁₄ClN₅O₄
• Purity: Min. 95%