Macropin 1
Ref. 3D-CRB1000053
1mg
254.00€
500µg
186.00€
Product Information
Name:Macropin 1
Synonyms:
- H-GFGMALKLLKKVL-NH2
Brand:Biosynth
Description:Macropin-1 (MAC-1) is an anti-microbial peptide (AMP) isolated from venom of the solitary bee Macropis fulvipes (Hymenoptera: Melittidae). MAC-1 has activity against both Gram-positive and Gram-negative bacteria, including drug-resistant strains. MAC-1 can inhibit biofilm formation in Staphylococcus aureus and Pseudomonas aeruginosa and also exhibits anti-fungal activity. MAC-1 has little to no haemolytic activity against human cells at microbiologically effective concentrations.Macropin acts by first binding to negatively charged bacterial membrane components- such as peptidoglycan (PTG) or lipopolysaccharide (LPS). Macropin then kills the bacteria by disrupting the outer bacterial membrane and depolarising the cytoplasmic membrane to cause cell penetration.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1,416.86 g/mol
Technical inquiry about: Macropin 1
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