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Isotocin
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Isotocin

Ref. 3D-CRB1000141

1mg
371.00 €
500µg
271.00 €
Estimated delivery in United States, on Friday 13 Dec 2024

Product Information

Name:
Isotocin
Synonyms:
  • [Cyc(1,6)]H-CYISNCPIG-NH2
Description:

Isotocin is a nonapeptide of the arginine vasopressin-oxytocin family produced exclusively in the preoptic area (POA) of teleosts. As a homologue of mammalian oxytocin, studying fish nonapeptides has shown that Isotocin mediates social and reproductive behaviour in fishes. Functional isotocin is stored in granules at the axon terminal with a carrier peptide, neurophysin. Stimuli leads to isotocin dissociation, to be released into the bloodstream or to cross over into the brain. It binds to G-protein coupled receptors (GPCRs), which subtype isotocin binds to defines the following physiological action. It, like other nonapeptides, is a neuromodulator in the CNS, but when distributed by the bloodstream, it acts as a peripheral hormone, such as regulating osmoregulation. Isotocin levels are sex-dependent and linked to the reproductive cycle.HPLC is a sensitive method to detect bioavailable isotocin and other nonapeptides. Measurement of mRNA levels of isotocin has been important to demonstrate the cyclical changes to regulate the endocrine calendar and diurnal rhythm. The level of isotocin is also considered a biomarker for aggression in behavioural indicators of fish welfare studies.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
966.14 g/mol
Color/Form:
Powder
MDL:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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