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Alpha-Factor
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Alpha-Factor

CAS: 59401-28-4

Ref. 3D-CRB1000148

1mg
271.00 €
5mg
522.00 €
10mg
861.00 €
25mg
994.00 €
Estimated delivery in United States, on Tuesday 3 Dec 2024

Product Information

Name:
Alpha-Factor
Synonyms:
  • H-WHWLQLKPGQPMY-OH
  • H-Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr-OH
  • Mating Factor .alpha.
  • a-Mating Factor, Yeast
  • alpha1-Mating factor Saccharomyces cerevisiae
  • L-tryptophyl-L-histidyl-L-tryptophyl-L-leucyl-L-glutaminyl-L-leucyl-L-lysyl-L-prolylglycyl-L-glutaminyl-L-prolyl-L-methionyl-L-tyrosine
  • Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr
Description:

The alpha factor pheromone arrests yeast in the G1 phase of their cell cycle, this allows the opposite mating type cells to synchronise. Alpha factor mating pheromone induces the expression of mating genes, changes in nuclear architecture, and polarizes growth toward the mating partner. STE2 encodes the alpha factor pheromone transmembrane G-protein coupled receptor (GPCR) found on mating-type-A cells in yeast. Alpha factor binds Ste2 and activates prototypic mitogen-activated protein kinase (MAPK) cascade. The dose of pheromone exposure differentially activates the MAPK Fus3 for alternate effects. A high dose of alpha factor leads to growth arrest and schmooing formation for mating, a lower dose causes elongated cell growth.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
1,683.97 g/mol
Formula:
C82H114N20O17S
Purity:
Min. 95%
Color/Form:
Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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