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LRRKtide
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LRRKtide

Ref. 3D-CRB1000328

1mg
271.00 €
5mg
626.00 €
10mg
911.00 €
25mg
1,169.00 €
500µg
198.00 €
Estimated delivery in United States, on Friday 13 Dec 2024

Product Information

Name:
LRRKtide
Synonyms:
  • H-RLGRDKYKTLRQIRQ-OHERM peptideERMtideLeucine-Rich Repeat Kinase substrateMoesinRLGRDKYKTLRQIRQ-acidH-Arg-Leu-Gly-Arg-Asp-Lys- Tyr-Lys-Thr-Leu-Arg-Gln-Ile-Arg-Gln-OHERM peptide
  • ERMtide
  • Leucine-Rich Repeat
Description:

LRRKtide (also called moesin) is a peptide substrate for leucine-rich repeat kinase 2 (LRRK2). The sequence of LRRKtide has been derived from the ERM proteins: Ezrin (amino acids 561-573), radixin (amino acids 558-570) and moesin (amino acids 539-553). These proteins influence cytoskeletal dynamics by anchoring the cytoskeleton to the plasma membrane. LRRK2 phosphorylates LRRKtide at its Thr558 site.LRRK2 is a large, ubiquitous protein of unknown function. LRRK2 has GTPase and kinase activity, and is located in multiple areas of the cell where it is found associated with intracellular membranes and vesicular structures. Its multiple cellular locations suggest that LRRK2 may be involved in several cellular pathways. LRRK2 is also found in most organs and mutations in LRRK2 have been identified in Parkinson's disease.This peptides has a non-amidated C-terminal end.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
1,930.1 g/mol
Color/Form:
Powder
MDL:
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Flash point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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