Hp1404
Ref. 3D-CRB1000537
1mg
254.00€
500µg
186.00€
Product Information
Name:Hp1404
Synonyms:
- H-GILGKLWEGVKSIF-NH2
Brand:Biosynth
Description:Antimicrobial peptides (AMP) are proving a lucrative area for antibiotics in the era of bacterial resistance. Of note, the scorpion Heterometrus petersii was found to produce Hp1404, an amphipathic cationic peptide with specific activity against Gram-positive bacteria- Hp1404 was shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA). The mode of action is by membrane penetration and disruption. MRSA did not gain resistance after several exposures to Hp1404 suggesting it may be a key agent against the rise of antibiotic resistance. Importantly, bacterial lethality was maintained with low toxicity to mammalian cells. Hp1404 is being used to generate analogues with reduced toxicity to mammalian cells and improved antimicrobial potency against a wider range of organisms.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1,544.9 g/mol
Color/Form:Powder
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