Thrombin Receptor Antagonist
Ref. 3D-CRB1000557
| 1mg | 198.00 € | ||
| 5mg | 371.00 € | ||
| 500µg | 136.00 € |
Product Information
- H-FLLRN-OH
Thrombin is the main effector of the coagulation cascade- it is a serine protease. Thrombin binds to active protease activated receptor 1 (PAR-1) which belongs to a subfamily of G-protein coupled receptors (GPCR). However, thrombin generated during cardiopulmonary bypass can activate PAR-1 leading to platelet dysfunction and unwanted bleeding. FLLRN is found to be a potent PAR-1 antagonist. Use of FLLRN and variants has aided the study of platelet aggregation dynamics. Further study may provide a suitable clinical application.
Chemical properties
Technical inquiry about: 3D-CRB1000557 Thrombin Receptor Antagonist
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