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PAR-4 Agonist (Mouse)
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PAR-4 Agonist (Mouse)

CAS: 245443-52-1

Ref. 3D-CRB1000559

1mg
271.00 €
500µg
198.00 €
Estimated delivery in United States, on Tuesday 3 Dec 2024

Product Information

Name:
PAR-4 Agonist (Mouse)
Synonyms:
  • H-GYPGKF-NH2
  • H-Gly-Tyr-Pro-Gly-Lys-Phe-Nh2
Description:

Thrombin is the main effector of the coagulation cascade- it is a serine protease. Thrombin binds to active protease activated receptor (PAR) which belongs to a subfamily of G-protein coupled receptors (GPCR). Thrombin activation of mouse PAR-4 reveals an amino terminus sequence of GYPGKF. This is the natural ligand for PAR-4. GYPGKF binds internally to the receptor and leads to signalling activation. Identification of GYPGKF as a PAR-4 agonist has allowed better understand of the function of PAR. Addition of GYPGKF to PAR-4 expressing cell lines achieved 55% of the maximal response of thrombin. GYPGKF can provide understanding of PAR-4 and a template for more potent agonists.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
666.3 g/mol
Formula:
C33H46N8O7
Color/Form:
Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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