SRC Substrate Peptide

Ref. 3D-CRB1000603

Product Information

• Name: SRC Substrate Peptide
• Synonyms: H-KVEKIGEGTYGVVYK-OH
• Brand: Biosynth
• Description: Src is a member of the Src family tyrosine kinases (SFKs), a large cytosolic, non-receptor, kinase family that controls multiple signalling pathways in animal cells. SFKs play key roles in cell morphology and differentiation, motility, proliferation and survival. Src contains an N-terminal 14-carbon myristoyl group, a unique segment, an SH3 domain, an SH2 domain, a protein-tyrosine kinase domain and a C-terminal regulatory tail. Src is expressed ubiquitously however it is seen at far higher levels in the brain, osteoclasts, and platelets. Src is a proto-oncogene and elevated levels of Src protein are seen in different tumours including: breast- lung- thyroid- glioblastoma- colorectal- pancreatic- prostate- gastric- biliary tract, ovarian and skin cancer. Src levels are often associated with tumour progression, metastasis and a poor clinical outcome and therefore Src has been investigated as a therapeutic target.

Chemical properties

• Molecular weight: 1,668.9 g/mol
• Color/Form: Powder