Ac-TTAI-NH2
Ref. 3D-CRB1000672
1mg
254.00€
500µg
186.00€
Product Information
Name:Ac-TTAI-NH2
Synonyms:
- Ac-TTAI-amideAcetyl-Thr-Thr-Ala-Ile-NH2LL30-34
Brand:Biosynth
Description:AAT is a highly abundant serine protease inhibitor primarily produced in the liver to protect the lung tissue. However, misfolding of AAT can result in significant liver disease, lung disease, and cancers. Defective AAT is characteristic of the misfolding protein diseases known as serpinopathies.Ion mobility mass spectrometry (IM-MS) was used to identify Ac-TTAI-amide as a ligand effecting α1-antitrypsin stability. Interaction of Ac-TTAI-amide with AAT results in increased stability and reduced polymerisation. Thus Ac-TTAI-amide is a useful target for further research in to serpinopathy management.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:445.3 g/mol
Color/Form:Powder
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