polyalanine peptide (pALA)
Ref. 3D-CRB1000678
| 1mg | 271.00 € | ||
| 500µg | 198.00 € |
Product Information
- H-AAADAAAAL-OH
The rise of antibiotic resistance has led to the search for new drug alternatives. Antimicrobial peptides (AMPs) have been identified as a lucrative area for molecule design. The polar fish Pleuronectes americanus expresses polyalanine peptide (pALA) which has been shown to be an AMP against biofilms, and gram-negative bacteria, while not being toxic to mammalian cells. pALA forms an alpha helical conformation that is effective at permeabilising the gram-negative bacteria membrane inducing fatal cell leakage. pALA provides a suitable model for molecule design to hopefully provide new drugs as we enter the post-antibiotic era.
Chemical properties
Technical inquiry about: 3D-CRB1000678 polyalanine peptide (pALA)
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