Angiotensin (Human, 1-7)

CAS: 51833-78-4

Ref. 3D-CRB1000803

Product Information

• Name: Angiotensin (Human, 1-7)
• Synonyms: H-DRVYIHP-OH
• Brand: Biosynth
• Description: Angiotensin 1-7 (Ang-(1-7)) is a component of the renin angiotensin system RAS. Ang-(1-7) is produced by angiotensin-converting enzyme 2 (ACE2), from the angiotensin II (Ang-II) peptide, as well as by prolylendopeptidase (PEP) and neutral endopeptidase (NEP) which produce Ang-(1-7) directly from angiotensin I (Ang-I).Ang-(1-7) broadly opposes Ang-II actions. Ang-(1-7) has vasodilatory and anti-oxidative effects, and exerts protective actions in hypertension, diabetes, and other cardiovascular disorders, Ang-(1-7) therefore represents a promising therapeutic target for cardiovascular and metabolic diseases. Ang-(1-7) exerts its actions via its G-protein-coupled receptor, Mas. This novel arm of the RAS has effects that counterbalance those mediated by the classical ACE/Ang-II pathway.

Chemical properties

• Molecular weight: 899.01 g/mol
• Formula: C₄₁H₆₂N₁₂O₁₁
• Purity: Min. 95%
• Color/Form: Powder