DAG peptide
Ref. 3D-CRB1000885
1mg
254.00€
500µg
186.00€
Product Information
Name:DAG peptide
Synonyms:
- [Cyc(1,9)]H-CDAGRKQKC-OHCDAGRKQKC-acid
- (Disulfide bridge: Cys1 - Cys9)H-Cys-Asp-Ala-Gly-Arg-Lys-Gln-Lys-Cys-OH
- (Disulfide bridge : Cys1 - Cys9)
Brand:Biosynth
Description:Cyclic DAG peptide targets connective tissue growth factor (CTGF/CCN2), present in the extracellular matrix, endothelial cells and overexpressed in several brain diseases. CTGF is a matricellular protein that acts as a regulator of several cellular functions, including cell adhesion, migration, mitogenesis, differentiation, and survival. CTGF is up regulated in Alzheimer's disease, Parkinson's disease, brain injury, glioblastoma, and cerebral infarction.DAG peptide has been shown to home to the brain in mouse models of glioblastoma, traumatic brain injury, and Parkinson's disease when exogenously delivered, making it an attractive target for the treatment of glioblastoma. DAG may be of use as a tool to enhance delivery of therapeutics and imaging agents to sites of brain diseases.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1,005.4 g/mol
Technical inquiry about: DAG peptide
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