Biotin-DAG Peptide
Ref. 3D-CRB1000886
| 1mg | 452.00 € | ||
| 500µg | 371.00 € |
Product Information
- [Cyc(1,9)]Biot-CDAGRKQKC-OHBiotin-CDAGRKQKC-acid
- (Disulfide bridge: Cys1 - Cys9)Biotin-Cys-Asp-Ala-Gly-Arg-Lys-Gln-Lys-Cys-OH
- (D isulfide bridge: Cys1 - Cys9 )a-Calcitonin gene-related peptide (mous
Cyclic DAG peptide targets connective tissue growth factor (CTGF/CCN2), present in the extracellular matrix, endothelial cells and overexpressed in several brain diseases. CTGF is a matricellular protein that acts as a regulator of several cellular functions, including cell adhesion, migration, mitogenesis, differentiation, and survival. CTGF is up regulated in Alzheimer's disease, Parkinson's disease, brain injury, glioblastoma, and cerebral infarction.DAG peptide has been shown to home to the brain in mouse models of glioblastoma, traumatic brain injury, and Parkinson's disease when exogenously delivered, making it an attractive target for the treatment of glioblastoma. DAG may be of use as a tool to enhance delivery of therapeutics and imaging agents to sites of brain diseases.
Chemical properties
Technical inquiry about: 3D-CRB1000886 Biotin-DAG Peptide
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
