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TAT-Beclin 1
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TAT-Beclin 1

Ref. 3D-CRB1000910

1mg
452.00 €
500µg
371.00 €
Estimated delivery in United States, on Friday 13 Dec 2024

Product Information

Name:
TAT-Beclin 1
Synonyms:
  • H-YGRKKRRQRRRGGTNVFNATFEIWHDGEFGT-OHYGRKKRRQRRRGGTNVFNATFEIWHDGEFGT-acidH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Thr- Asn-Val-Phe-Asn-Ala-Thr-Phe-Glu-Ile-T rp-His-Asp-Gly-Glu-Phe-Gly-Thr-OH
Description:

TAT-Beclin Scrambled is a peptide derived from a region of Beclin 1, which interacts with a newly identified negative regulator of autophagy, GAPR-1 (also called GLIPR2) to act as a potent inducer of autophagy. Autophagy is an essential process that maintains cellular homeostasis and carries out lysosome-mediated degradation of unwanted proteins in the cytoplasm. It is often examined when looking at disease pathways because of this regulatory function. While the immune system initiates the removal of viruses and pathogens through the autophagic pathway, some viruses (such as HIV) are able to evade this process.TAT (47-57) is present due to its properties as a cell penetrating cationic peptide (CPP). It derived from the N-terminus of the Tat protein, which is a trans-activator of the transcription protein present in the human immunodeficiency virus (HIV). As a CPP, TAT (47-57) is able facilitate the delivery of the Beclin scrambled protein across the plasma membrane.This peptide contains a GG linker between the C-terminus of TAT (47-57) and the N-terminus of Beclin 1.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
3,738.9 g/mol
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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