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MAGEA4 (230-239) Light
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MAGEA4 (230-239) Light

Ref. 3D-CRB1000938

1mg
271.00 €
500µg
198.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024

Product Information

Name:
MAGEA4 (230-239) Light
Synonyms:
  • GVYDGREHTV-acidH-Gly-Val-Tyr-Asp-Gly-Arg-Glu-His-Thr-Val-OH
Description:

Melanoma-associated antigen As (MAGEA) are a large family of tumour-associated antigens and a subclass of the larger family of cancer testis antigens (CTAs). These proteins are tumour antigens expressed in a variety of malignant tumours including: bladder- lung- skin and breast malignancies. In healthy tissue however their expression is restricted to germ cells of the testis, nervous system, foetal ovaries and placenta. In cancer cells, the MAGEA family proteins support growth, survival and metastasis, and contribute actively to malignancy. They are also involved in the regulation of the tumour suppressor protein p53 pathway and in regulating ubiquitin signalling in cancer cells. MAGEA expression is linked to poor prognosis in cancer patients. MAGEA subfamily proteins are recognized by cytotoxic T lymphocytes and evoke a strong T cell reactivity against autologous tumour cells in culture.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
1,131.5 g/mol
Formula:
C48H73N15O17
Color/Form:
Powder
MDL:
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EINECS:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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