2-Furoyl-LIGRL-amide

Ref. 3D-CRB1001017

Product Information

• Name: 2-Furoyl-LIGRL-amide
• Synonyms: 2furoyl-LIGRL-NH2
• Brand: Biosynth
• Description: PAR2 plays a particular role in protecting the gastric mucosa mediated by capsaicin-sensitive sensory neurons. PAR2 also serves to aid in gut smooth muscle motility- colon inflammation pathway- hyperalgesia and is also anti-inflammatory in other circumstances.Development of selective agonists for PAR2 are crucial for research. (2-Furoyl)-LIGRL-amide is a far more potent agonist than the native PAR2 activating peptide SLIGRL-NH2. In mice, oral administration conferred cytoprotection from gastrointestinal lesions. However, it was inhibited by capsaicin pre-treatment.

Chemical properties

• Molecular weight: 663.4 g/mol