Cyclo(RGDfK)
Ref. 3D-CRB1001046
| 1mg | 452.00 € | ||
| 500µg | 371.00 € |
Product Information
- [LacN(0,5)]RGD(dF)KCyclo(RGDfK) where f is D-PhenylalanineCyclo(Arg-Gly-Asp-[D-Phe]-Lys)where D-Phe is D-Phenylalaninec(RGDfK)c( -RGDfK)
The cyclic pentapeptide cyclo(Arg-Gly-Asp-[D-Phe]-Lys) is a highly potent and selective inhibitor for the alphavβ3 integrin receptor. A related compound, cyclo(Arg-Gly-Asp-[D-Phe]-Val), is a promising anticancer drug candidate- it inhibits angiogenesis and induces apoptosis in vascular cells.Cyclic RGD-containing peptides are selective antagonists of integrins, proteins that play important roles in cell-cell and cell-matrix interactions. In a suitably labelled form, these peptides may serve as useful tools for diagnostic imaging and peptide targeted therapy of some types of cancer.
Chemical properties
Technical inquiry about: 3D-CRB1001046 Cyclo(RGDfK)
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