Human PD - L1 inhibitor V

Ref. 3D-CRB1001116

Product Information

• Name: Human PD - L1 inhibitor V
• Synonyms: H-LDYVNRRKMYQ-OH
• Brand: Biosynth
• Description: PD-1 inhibitors and PD-L1 inhibitors are a group of checkpoint inhibitors being developed for the treatment of cancer.PD-1 and its ligand PD-L1 are critical in regulating T cell activation, tolerance and immunopathology. PD-1 is an immune checkpoint and guards against autoimmunity through two mechanisms. First, it promotes apoptosis of antigen-specific T-cells in lymph nodes. Second, it reduces apoptosis in regulatory T cells. Several types of cancer cells overexpress PD-L1 in order to escape from the PD-1/PD-L1 immunosurveillance mechanism. In this way, Human PD - L1 inhibitor V could be used in the treatment of cancers that overexpress PD-L1.

Chemical properties

• Molecular weight: 1,484.8 g/mol
• Color/Form: Powder