gp91 ds-TAT
Ref. 3D-CRB1001119
| 1mg | 271.00 € | ||
| 500µg | 198.00 € |
Product Information
- H-YGRKKRRQRRRCSTRIRRQL-NH2YGRKKRRQRRRCSTRIRRQL-amideH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Ser-Thr-Arg-Ile-Arg-Arg-Gln- Leu-NH2
The gp91 ds-TAT peptide is composed of a gp91phox sequence conjugated to the human immunodeficiency virus-TAT peptide. The TAT sequence facilitates its entry into all cells, hence it is a cell-penetrating peptide. The gp91 peptide is the haem binding sub-unit of the superoxide-generating NADPH oxidase. As a result, the gp91 ds-TAT peptide can be used as a selective inhibitor of NADPH oxidase assembly.Recent studies have shown that gp91 ds-TAT can increase blood nitric oxide bioavailability in hind limb ischaemia and reperfusion by inhibiting NADPH oxidase.
Chemical properties
Technical inquiry about: 3D-CRB1001119 gp91 ds-TAT
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