gp91 ds-TAT

Ref. 3D-CRB1001119

Product Information

• Name: gp91 ds-TAT
• Synonyms: H-YGRKKRRQRRRCSTRIRRQL-NH2YGRKKRRQRRRCSTRIRRQL-amideH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Ser-Thr-Arg-Ile-Arg-Arg-Gln- Leu-NH2
• Brand: Biosynth
• Description: The gp91 ds-TAT peptide is composed of a gp91phox sequence conjugated to the human immunodeficiency virus-TAT peptide. The TAT sequence facilitates its entry into all cells, hence it is a cell-penetrating peptide. The gp91 peptide is the haem binding sub-unit of the superoxide-generating NADPH oxidase. As a result, the gp91 ds-TAT peptide can be used as a selective inhibitor of NADPH oxidase assembly.Recent studies have shown that gp91 ds-TAT can increase blood nitric oxide bioavailability in hind limb ischaemia and reperfusion by inhibiting NADPH oxidase.

Chemical properties

• Molecular weight: 2,671.6 g/mol
• Color/Form: Powder