Shepherdin (79 - 87)
Ref. 3D-CRB1001139
1mg
254.00€
500µg
186.00€
Product Information
Name:Shepherdin (79 - 87)
Synonyms:
- H-KHSSGCAFL-OH
Brand:Biosynth
Description:Shepherdin is an antagonist of the interaction between the apoptosis protein, survivin, and the molecular chaperone, heat shock protein 90 (Hsp90). The sequence of shepherdin corresponds to the site where Hsp90 binds to survivin. Shepherdin therefore has high affinity for Hsp90 and thus disrupts survivin binding and acts as an inhibitor of Hsp90 ATPase function by competing with ATP.The survivin-Hsp90 complex is a regulator of cell proliferation and cell viability in cancer tissue. Shepherdin has anti-cancer properties and can significantly suppress the growth of lung cancer cell lines and acute myeloid leukaemia (AML) by inducing apoptosis.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:948.4 g/mol
Color/Form:Powder
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