TAT - GluR23Y
Ref. 3D-CRB1001142
1mg | 271.00 € | ||
500µg | 198.00 € |
Product Information
- H-YGRKKRRQRRRYKEGYNVYG-OHYGRKKRRQRRRYKEGYNVYG-acidH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Tyr-Lys-Glu-Gly-Tyr-Asn-Val-Tyr-Gl y-OH
TAT-GluR23Y is a cell penetrating peptide that inhibits phosphorylation of AMPA receptor endocytosis.Recent studies have shown that AMPA receptor endocytosis, which is a cellular mechanism underlying the formation of LTD, plays a critical role in facilitating initial extinction of learned fear. Tat-Glur23Y can block regulated AMPA and thereby prevents long-term depression (LTD) in structures such as the nucleus accumbens and dorsal hippocampus.
Chemical properties
Technical inquiry about: 3D-CRB1001142 TAT - GluR23Y
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